The Belgian and the French internationals return to Anfield to face their former club in this weekend premier league game.
Benteke returns to Anfield for the first time since ending his one season stay at the club last summer with a £27million move to Selhurst Park.
Benteke has scored 14 goals this season four more goals than when he was managed under Klopp last season. He has scored three goals in his last four games.
Benteke has been thorn in the flesh for Liverpool since he left for crystal palace. Klopp admits that he likes scoring against Liverpool Benteke has scored five times in seven appearances.
"When the ball is in the air he is the main threat because he is unbelievable and we felt it all the time in training when he was here," Klopp said.
"He has scored 14 goals this season so he is another player with confidence and on a good run.
"Always when you play against players like these type of players who are tall, good with their backs to the goal, you have to avoid the crosses and the passes.
"If we let them cross 50 balls it is pretty likely he will have a few dangerous headers but that is not his only strength.
"You have to avoid passes in this area but not only for him; if you only concentrate on Christian then (Wilfried) Zaha, (Andros) Townsend are around you.
"They have one of the best offensive lines in the Premier League and we respect this."
While Sakho has done much to ease Palace’s relegation worries since his arrival to Selhurst Park.
The France international, who has helped Palace keep four clean sheets in seven matches - from which they have taken 16 points and beaten Chelsea and Arsenal - will be ineligible against his parent club and that gives them a problem
The French international fell out of favour with Klopp for him failing a drug test and he was banished to the under 23s. Benteke went on loan to crystal palace to re-establish his reputation.
"He is a good player and of course we watch all the games, especially in preparation for this game," added Klopp.
"He is a very good defender, especially when you defend deep like Crystal Palace do often.
"He is a very strong boy with good tackles and blocks so having a player like him in the team is very good.
At this point of the season Liverpool are having defensive issue. Defenders like Joel Matip and Ragnar Klavan - plus midfielder-turned-auxiliary-centre-back Lucas Leiva - unable to train this week because of minor injuries. Sakho would have been a solid performer and a main player for them at the defensive line had it been he hasn’t been loaned out.