Real Madrid will be facing Atletico in the Champions League Semi Final while Juventus have a date with Monaco.
The Madrid sides are facing off in the competition for the third time in four seasons, with the previous two encounters taking place in the final.
Real Madrid emerged winners in both matches.
Zinedine Zidane's side will become the first club to retain the trophy in the Champions League era should they make it all the way this year.
French side AS Monaco, meanwhile, will take on Italian club Juventus in the other last-four tie, the first leg being played at the Stade Louis II.
The first legs of the Champions League semi-finals will take place on May 2 and 3, and the second legs played on May 9 and 10.
The final is set to take place at Cardiff's Millennium Stadium on Saturday, June 3.